"Some Like It" by Amerie seems to be a flirtatious and confident anthem where the singer asserts her desires and expects the same level of enthusiasm from her love interest. She presents herself as someone who is full of excitement and adventure, willing to show her companion new experiences and sensations. The repetition of "whatcha gonna do with it?" suggests that she wants to know how her love interest will respond to her advances and whether they are willing to engage in the same level of passion and exploration.

The catchy chorus emphasizes that while some people may merely like or appreciate her boldness and energy, she is seeking someone who truly loves and appreciates it. She does not want to waste time waiting around and suggests that if someone is hesitant or scared, she understands, but also highlights that it is not impossible to embrace the excitement she offers.

In the bridge, Amerie questions what her love interest will do when she signals the end of the encounter by saying goodnight. She acknowledges that opportunities like this don't come often and wants her love interest to recognize the value of the moment. The song ends with the repeated question of what they are going to do, leaving the listener to contemplate the response and the potential outcome of their interaction.