The song "Better Lose Yourself [Eminem Diss #3]" by Benzino is a diss track aimed at rapper Eminem. The lyrics contain aggressive and confrontational language towards Eminem, highlighting a personal and professional rivalry between the two artists.

In the song, Benzino accuses Eminem of being unable to handle a real-life confrontation or street beef. He challenges Eminem to a fight and boasts about his ability to physically harm him. Benzino also attacks Eminem's lyrical abilities, claiming that he was a backstreet boy who learned to rap and that his gun is empty, implying that he is not as tough as he portrays himself to be.

Benzino references specific incidents involving Eminem, such as his performance with Elton John at the Grammy Awards and the ICP (Insane Clown Posse) allegedly assaulting Eminem. He also mocks Eminem's personal life, mentioning his wife and children, and suggests that Eminem's baby mom's flies to Boston, implying that she is cheating on him.

Throughout the song, Benzino asserts his dominance over Eminem, claiming that he runs the streets and has control over the rap game. He dismisses other artists that Eminem has dissed, such as Fred Durst and Britney Spears, and asserts that Eminem is not living up to his reputation as the best rapper.

The overall tone of the song is confrontational, aggressive, and aimed at challenging Eminem's credibility, both as a rapper and as a person. It portrays Benzino as a street-oriented individual who is unafraid to physically harm Eminem and his associates.