In "Hurt Me", Juice WRLD talks about the effects of drugs on his life and relationships. He discusses how he feels like a different person when he's under the influence and how it affects his driving. Despite these dangers, he asserts that the drugs won't hurt him, highlighting how he uses them to escape his pain and problems.

Juice WRLD also talks about his ex-girlfriend calling him, but he remains unfazed, stating that she can't hurt him. He emphasizes that he has done everything on his own and he shows no mercy to those who try to bring him down.

The song concludes with a repetition of the opening lines, signifying that Juice WRLD is trapped in a cycle of addiction and self-destruction. Overall, "Hurt Me" is a song about the destructive effects of substance abuse and how it can damage one's emotional and physical well-being.