The song "SICKO MODE" by Travis Scott ft. Drake, is largely about their success and fame as rappers. The lyrics describe their luxurious lifestyle with references to expensive brands and lavish hotels. The first verse talks about their way of life as successful rappers with nothing to stop them, and they're constantly on the move with their entourage and huge wealth.

The bridge of the song features a sample from Big Hawk asking who is going to win in their quest to obtain success, with Swae Lee adding that they're all in too deep, where the success has come to overrule any other motivations.

The second verse talks about how different Travis Scott is from others who follow the norm. He mentions how most women don't understand him, but all of his "girls" are attracted to his unique style. Scott talks about how he made a lot of money producing music and how he feels his exes should all be grouped together because they are all trying to keep him in their lives. The verse ends with him taking a woman to a Miami hotel. The chorus sung by Drake describes how Travis Scott is now living an impressive life as a result of becoming a renowned rapper.

The bridge and chorus come again, emphasizing the idea that the success they've attained and their lifestyles are something they fiercely defend.

In the last verse, Travis talks about his fame and how the people around him have prospered as a result of his wealth. He comments on the unusual journey he took to get to the top and speaks of how proud he is of his daughter and how she will learn more about the kind of work it took and will someday appreciate it. The song ends with the conquest being long-term, Travis mentions how he has covered magazines with his ex-girlfriend and presently, he has so much more.