"Go Loko" by YG ft. Jon Z and Tyga is a song about having wild and crazy experiences with women. The lyrics have a strong focus on their party lifestyle and living in the moment, particularly by engaging in sexual activity with these women. The chorus refers to YG's girlfriend as "my bitch" and how she "goes loco" by bouncing her ass like a lolo. The verses by YG and Tyga further depict their desire for uninhibited sexual encounters with women who are not afraid to take risks, whether it be handcuffing or partying until the sun comes up. Jon Z's verse is in Spanish and makes reference to his love for a Latina woman who he describes in detail. The song overall is an expression of sexual desire and the excitement that comes with living life on the edge.